产品名称：Phospho-PAX7(Ser203) Antibody/Affinity/磷酸化/AF7084/100ul现货

别名:

FLJ37460; HUP1; OTTHUMP00000002534; Paired box 7; Paired box gene 7; Paired box homeotic gene 7; Paired box protein Pax-7; Paired domain gene 7; Paired domain gene HuP1; Pax7; PAX7 transcriptional factor; PAX7/FKHR fusion gene, included; PAX7_HUMAN; PAX7B; RGD1564360; RMS2;

应用:

WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

反应种属:

Human,Mouse

纯化:

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

表位:

Phospho-PAX7(Ser203) Antibody detects endogenous levels of PAX7 only when phosphorylated at Ser203

**原:

A synthesized peptide derived from human PAX7 around the phosphorylation site of Ser203

研究领域:

· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer

功能:

Transcription factor playing a role in myogenesis through regulation of muscle precursor cells proliferation.

细胞定位:

Nucleus;

亚结构:

Can bind to DNA as a heterodimer with PAX3. Interacts with PAXBP1; the interaction links PAX7 to a WDR5-containing histone methyltransferase complex (By similarity). Interacts with DAXX (PubMed:10393185).

同源性:

Belongs to the paired homeobox family.

蛋白序列:

        10         20         30         40         50
MAALPGTVPR MMRPAPGQNY PRTGFPLEVS TPLGQGRVNQ LGGVFINGRP 
        60         70         80         90        100
LPNHIRHKIV EMAHHGIRPC VISRQLRVSH GCVSKILCRY QETGSIRPGA 
       110        120        130        140        150
IGGSKPRQVA TPDVEKKIEE YKRENPGMFS WEIRDRLLKD GHCDRSTVPS 
       160        170        180        190        200
GLVSSISRVL RIKFGKKEEE DEADKKEDDG EKKAKHSIDG ILGDKGNRLD 
       210        220        230        240        250
EGSDVESEPD LPLKRKQRRS RTTFTAEQLE ELEKAFERTH YPDIYTREEL 
       260        270        280        290        300
AQRTKLTEAR VQVWFSNRRA RWRKQAGANQ LAAFNHLLPG GFPPTGMPTL 
       310        320        330        340        350
PPYQLPDSTY PTTTISQDGG STVHRPQPLP PSTMHQGGLA AAAAAADTSS 
       360        370        380        390        400
AYGARHSFSS YSDSFMNPAA PSNHMNPVSN GLSPQVMSIL GNPSAVPPQP 
       410        420        430        440        450
QADFSISPLH GGLDSATSIS ASCSQRADSI KPGDSLPTSQ AYCPPTYSTT 
       460        470        480        490        500
GYSVDPVAGY QYGQYGQTAV DYLAKNVSLS TQRRMKLGEH SAVLGLLPVE 
TGQAY                                             

保存说明:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt