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  • 产品名称:Phospho-TRIM32(Ser339) Antibody/Affinity/磷酸化/AF7074/100ul现货

  • 产品型号:AF7074
  • 产品厂商:Affinity
  • 产品价格:2500
  • 折扣价格:0
  • 产品文档:
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简单介绍:
Phospho-TRIM32(Ser339) Antibody/Affinity/磷酸化/AF7074/100ul现货 Affinity全球*全*新磷酸化抗体,可出具HPLC/MS检测报告,WB检测采用封闭钛验证。ELISE保证,IHC验证人大小鼠超过70种不同组织。 Phospho-TRIM32(Ser339) Antibody/Affinity/磷酸化/AF7074/100ul现货 Phospho-TRIM32(Ser339) Antibody/Affinity/磷酸化/AF7074/100ul现货
详情介绍:

Phospho-TRIM32(Ser339) Antibody/Affinity/磷酸化/AF7074/100ul现货


别名:

72 kda Tat interacting Protein; 72 kDa Tat-interacting protein; BBS11; E3 ubiquitin-protein ligase TRIM32; HT2A; LGMD2H; Limb girdle muscular dystrophy 2H (autosomal recessive); Limb girdle muscular dystrophy 2H; Muscular dystrophy Hutterite type; TAT interactive protein 72KD; TATIP; TRI32_HUMAN; Trim32; Tripartite Motif Containing Protein 32; Tripartite motif-containing protein 32; Zinc finger protein HT2A;

应用:

WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

反应种属:

Human,Mouse

纯化:

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

表位:

Phospho-TRIM32(Ser339) Antibody detects endogenous levels of TRIM32 only when phosphorylated at Ser339

**原:

A synthesized peptide derived from human TRIM32 around the phosphorylation site of Ser339

研究领域:

· Genetic Inion Processing > Folding, sorting and degradation > Ubiquitin ted proteolysis(查看通路图)

功能:

Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin) and promotes its degradation. May ubiquitinate BBS2. May play a significant role in ting the biological activity of the HIV-1 Tat protein in vivo. Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo.

细胞定位:

Cytoskeleton;Cytosol;Nucleus;

Extracellular region or secretedCytosolPlasma membraneCytoskeletonLysosomeEndosomePeroxisomeERGolgi apparatusNucleusMitochondrionManual annotationAutomatic computational assertionGraphics by Christian Stolte

翻译后修饰:

Ubiquitinated.

组织特异性:

Spleen, thymus, prostate, testis, ovary, intestine, colon and skeletal muscle.

亚结构:

Interacts with DTNBP1. It self-associates.

同源性:

Belongs to the TRIM/RBCC family.

Protein BLAST With

蛋白序列:

        10         20         30         40         50
MAAAAASHLN LDALREVLEC PICMESFTEE QLRPKLLHCG HTICRQCLEK 
        60         70         80         90        100
LLASSINGVR CPFCSKITRI TSLTQLTDNL TVLKIIDTAG LSEAVGLLMC 
       110        120        130        140        150
RSCGRRLPRQ FCRSCGLVLC EPCREADHQP PGHCTLPVKE AAEERRRDFG 
       160        170        180        190        200
EKLTRLRELM GELQRRKAAL EGVSKDLQAR YKAVLQEYGH EERRVQDELA 
       210        220        230        240        250
RSRKFFTGSL AEVEKSNSQV VEEQSYLLNI AEVQAVSRCD YFLAKIKQAD 
       260        270        280        290        300
VALLEETADE EEPELTASLP RELTLQDVEL LKVGHVGPLQ IGQAVKKPRT 
       310        320        330        340        350
VNVEDSWAME ATASAASTSV TFREMDMSPE EVVASPRASP AKQRGPEAAS 
       360        370        380        390        400
NIQQCLFLKK MGAKGSTPGM FNLPVSLYVT SQGEVLVADR GNYRIQVFTR 
       410        420        430        440        450
KGFLKEIRRS PSGIDSFVLS FLGADLPNLT PLSVAMNCQG LIGVTDSYDN 
       460        470        480        490        500
SLKVYTLDGH CVACHRSQLS KPWGITALPS GQFVVTDVEG GKLWCFTVDR 
       510        520        530        540        550
GSGVVKYSCL CSAVRPKFVT CDAEGTVYFT QGLGLNLENR QNEHHLEGGF 
       560        570        580        590        600
SIGSVGPDGQ LGRQISHFFS ENEDFRCIAG MCVDARGDLI VADSSRKEIL 
       610        620        630        640        650
HFPKGGGYSV LIREGLTCPV GIALTPKGQL LVLDCWDHCI KIYSYHLRRY 
STP                                             

保存说明:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt


Phospho-TRIM32(Ser339) Antibody/Affinity/磷酸化/AF7074/100ul现货Phospho-TRIM32(Ser339) Antibody/Affinity/磷酸化/AF7074/100ul现货

Phospho-TRIM32(Ser339) Antibody/Affinity/磷酸化/AF7074/100ul现货Phospho-TRIM32(Ser339) Antibody/Affinity/磷酸化/AF7074/100ul现货

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